What is plasma coagulation

Information on donating blood

A good half of the blood (55%) is a clear, yellowish liquid: the plasma. The plasma itself consists of 91% water. 9% are nutrients, hormones, minerals and at least 120 different proteins, which are essential for blood clotting and defense against infections, for example.

Life-saving drugs can be made from more than a quarter of proteins, e.g. preparations made from

  • Antibodies (= immunoglobulins): They are used for chronic weaknesses of the immune system and acute diseases such as hepatitis, rabies, tetanus. Antibodies catch pathogens and render them harmless. In pregnancy, they prevent the threat of Rh factor intolerance between mother and child.
  • Coagulation Factors: Together with the blood platelets, they make it possible for hemophiliacs to stop bleeding after injuries and curb blood loss. Around 6,000 people in Germany suffer from severe congenital haemophilia A (factor 8 deficiency). Until the 1950s, these hemophiliacs were hardly older than 18 years. Since 1972 it has been possible to produce factor 8 in concentrated form from human blood plasma. As a result, hemophiliacs now have almost the same life expectancy as other people. These patients are also treated in the Haemophilia Center at the Saarland University Hospital.
  • Albumin: This protein is primarily responsible for the transport of metabolic products and stabilizes the distribution of fluids between blood vessels and tissue. Album entries are indispensable in the case of accident shock, burns, kidney damage or major operations, for example.
  • Fibrin glue: This is required, among other things, for the treatment of internal injuries or for local wound closure.